Kinam Park Publications

Publications

Articles

Microparticle Formulations

Park, K.: Nanotechnology: What it can do for drug delivery, J. Control. Release, 120: 1-3, 2007.
Acharya, G., Shin, C.S., McDermott, M., Mishra, H., Park, H., Kwon, I.C., and Park, K.: The hydrogel template method for fabrication of homogeneous nano/microparticles, J. Control. Release, 141: 314-319, 2010.
Acharya, G., Shin, C.S., Vedantham, K., McDermott, M., Rish, T., Hansen, K., Fu, Y. and Park, K.: A Study of Drug Release from Homogeneous PLGA microstructures, J. Control. Release,146: 201-206, 2010.
Kim, K., Kim, J.H., Park, H., Kim, Y.-S., Park, K.S., Nam, H., Lee, S., Park, J.H., Park, R.-W., Kim, I.-S., Choi, K., Kim, S.Y., Park, K. and Kwon, I.C.: Tumor-homing multifunctional nanoparticles for cancer theragnosis: Simultaneous diagnosis, drug delivery, and therapeutic monitoring, J. Control. Release, 146: 219-227, 2010.
Ye, M., Kim, S.W., and Park, K.: Issues in long-term protein delivery using biodegradable microparticles, J. Control. Release, 156: 241-260, 2010.

Polymer Micelles Back to Top

Saravanakumar, G., Min, H.H., Min, D.S., Kim, A.Y., Lee, C.M., Cho, Y.W., Lee, S.C., Kim, K., Jeong, S.Y., Park, K., Park, J., and Kwon, I.C.: Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paxclitaxel: Synthesis, characterization, and in vivo biodistribution, J. Control. Release, 140: 210-217, 2009.
Saravanakumar, G., Choi, K.Y., Yoon, H.Y., Kim, K., Park, J.H., Kwon, I.C., Park, K.: Hydrotropic hyaluronic acid conjugates: Synthesis, characterization, and implications as a carrier of paclitaxel. Int. J. Pharm., 394: 154-161, 2010.
Kim, J.Y., Kim, S.W., Papp, M., Park, K., and Pinal, R.: Hydrotropic solubilization of poorly water-soluble drugs, J. Pharm. Sci. 99: 3953-3965, 2010.
Chen, H., Kim, S., Li, L., Wang, S., Park, K., Cheng, J-X.: Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Förster resonance energy transfer imaging, Proc. Natl. Acad. Sci. USA, 105 (18): 6596-6601, 2008.
Chen, H., Kim, S., He, W., Wang, H., Low, P.S., Park, K., and Cheng, J-X.: Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo förster resonance energy transfer imaging, Langmuir, 24: 5213-5217, 2008.
Shi, Y., Kim, S.W., Huff, T.B., Borgens, R.B., Park, K., Shi, R., and Cheng, J.-X.: Effective repair of traumatically injured spinal cord by nanoscale block copolymer micelles, Nature Nanotech, 5: 80-87, 2010.
Kim, J.Y., Kim, S.W., Pinal, R., and Park, K.: Hydrotropic polymer micelles as versatile vehicles for delivery of poorly water-soluble drugs, J. Control. Release, 152: 13-20, 2011.

Targeted Drug Delivery Back to Top

Bae, Y.H. and Park, K.: Targeted Drug Delivery to Tumors: Myths, Reality, and Possibility, J. Control. Release, 153: 198-205, 2011.
Lee, S.J., Koo, H., Lee, D.E., Min, S., Lee, S., Chen, X., Choi, Y., Leary, J.F., Park, K., Jeong, S.Y., Kwon, I.C., and Choi, K.: Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system, Biomaterials, 32: 4021-4029, 2011.

Oral Formulations Back to Top

Jeong, S.H., Takaishi, Y., Fu, Y., and Park, K.: Materials for making fast dissolving tablets by compression method, J. Mater. Chem. 18: 3527-3535, 2008.
Jeong, S.H. and Park, K.: Development of sustained release fast-disintegrating tablets using various polymer-coated ion-exchange resin complexes, Int. J. Pharm., 353: 195-204, 2008.
Jeong, S.H. and Park, K.: Drug loading and release properties of ion-exchange resin complexes as a drug delivery matrix, Int. J. Pharm., 361: 26-32, 2008.
Wen, H., Morris, K., and Park, K.: Synergic effects of polymeric additives on dissolution and crystallization of acetaminophen, Pharm. Res., 25: 349-358, 2008.
Park, Kyeongsoon, and Park, Kinam: Oral protein delivery: Current status and future prospect, Reactive and Functional Polymers, 71: 280-287, 2011.

Drug-eluting Stents Back to Top

Finkelstein, A., Mcclean, D., Kar, S., Takizawa, K., Vargeese, K., Baek, N., Park, K., Fishbein, M.C., Makkar, R., Litvack, F., and Eigler, N.L. Local drug delivery via a coronary stent with programmable release pharmacokinetics. Circulation 107: 777-784 2003.
Kang, E., Wang, H., Kwon, I.K., Robinson, J., Park, K. and Cheng, J-X.: In situ visualization of paclitaxel distribution and release by coherent anti-Stokes Raman scattering microscopy, Anal. Chem., 78: 8036-8043, 2006.
Kang, E., Robinson, J., Park, K., and Cheng, J-X.: Paclitaxel distribution in poly(ethylene glycol) / poly(lactide-coglycolic acid) blends and its release visualized by coherent anti-Stokes Raman scattering microscopy, J. Control. Release, 122: 261-268, 2007.
Kang, E., Wang, H., Kwon, I.K., Song, Y-H., Kamath, K., Miller, K.M., Barry, J., Cheng, J-X., and Park, K.: Application of coherent anti-Stokes Raman scattering microscopy to image the changes in a paclitaxel-poly(styrene-b-isobutylene-b-styrene) matrix pre and post drug elution, J. Biomed. Mater. Res. A, 87: 913-920, 2008.
Kang, E., Vedantham, K., Long, X., Dadara, M., Kwon, I.K., Sturek, M., and Park, K.: A drug-eluting stent for delivery of signal pathway-specific 1,3-dipropyl-8-cyclopentyl xanthine (DPCPX), Molecular Pharmaceutics, 6(4): 1110-1117, 2009.

Smart Polymers & Hydrogels Back to Top

Books

Park, K., Shalaby, S.W.S., and Park, H.: Biodegradable Hydrogels for Drug Delivery, Technomic Publishing Co., Inc., Lancaster, PA, 1993, 252 pages.
Ottenbrite, R., Hwang, S., and Park, K., Eds.: Hydrogels and Biodegradable Polymers for Bioapplications(ACS Symposium Series 627), American Chemical Society, Washington, DC, 1996, 268 pages.
Park, K., Ed.: Controlled Drug Delivery: Challenges and Strategies, American Chemical Society, Washington, DC, 1997, 629 pages.
Park, K. and Mrsny, R., Eds.: Controlled Drug Delivery: Designing Technologies for the Future (ACS Symposium Series 752), American Chemical Society, Washington, DC, 2000, 459 pages.
Park, K.D., Kwon, I.C., Yui, N., Jeong, S.Y. and Park, K., Eds.: Biomaterials and Drug Delivery toward New Millennium, Han Rim Won Publishing Co., Seoul, Korea, 2000, 691 pages.
Park, K. Ed., Protein- and Cell-Repellent Surfaces, Colloids and Surfaces B: Biointerfaces, Elsevier Science, Vol. 18 (No. 3-4), 2000.
Park, K., Ed., Recent Developments in Hydrogels, Advanced Drug Delivery Reviews, Elsevier Science,Vol. 54, 2001.
Yui, N., Mrsny, R., and Park, K., Eds.: Flash polymers and hydrogels: Understanding and designing the fast-responsive polymeric systems, CRC Press, Boca Raton, FL, 2004. 452 pages.
Morishita, M. and Park, K., Eds.: Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development, Informa Healthcare, New York, NY, 2009, 544 pages.
Wen, H. and Park, K, Eds.: Oral Controlled Release Formulation Design and Drug Delivery, John Wiley & Sons, New York, NY, 2010. 363 pages.

JCR Cover Stories

Kinam Park: Luciferin liposomes for enhanced in vivo bioluminescence, J. Control. Release 141, 109, 2010.
Daan J.A. Crommelin, Kinam Park, and Alexander Florence: Pharmaceutical nanotechnology: Unmet nees in drug delivery, J. Control. Release 141, 263-264, 2010.
Kinam Park: Endocytic uptake and intracellular trafficking of poly(amidoamine)s, J. Control. Release 142, 1, 2010.
Kinam Park: To PEGylate or not to PEGylate, that is not the question, J. Control. Release 142, 147-148, 2010.
Kinam Park: Systemic siRNA Delivery Using Biocompatible Calcium Phosphate Nanoparticles, J. Control. Release 142, 295, 2010.
Kinam Park: Monitoring intracellular degradation of exogenous DNA by FCS and FCCS, J. Control. Release 143, 1, 2010.
Kinam Park: Tumor regression after systemic administration of transferrin-targeted TNFa plasmid- dendrimer conjugates, J. Control. Release 143, 167, 2010.
Kinamm Park: Efficient delivery of VEGF via heparin-functionalized nanoparticle–fibrin complex, J. Control. Release 143, 281, 2010.
Kinam Park: Safe and effective gene delivery by hybrid polymer-virus vectors, J. Control. Release 144, 1, 2010.
Kinam Park: Nano is better than micro for targeted vaccine delivery, J. Control. Release 144, 117, 2010.
Kinam Park: In vivo MRI analysis of intracellular trafficking of paramagnetically labeled liposomes, J. Control. Release 144,269 , 2010.
Kinam Park: Efficient oral delivery of paclitaxel using cyclodextrin complexes, J. Control. Release 145, 1, 2010.
Kinam Park: A new ligand for targeted drug delivery to tumor stromal cells, J. Control. Release 145, 75, 2010.
Kinam Park: Drug release coating for reduced tissue reaction to implanted neuroprostheses, J. Control. Release 145, 177, 2010.
Kinam Park: Positron emission tomography imaging for study of intestinal insulin absorption, J. Control. Release 146, 1, 2010.
Ralph Lipp, Randall Mrsny, and Kinam Park: Seventh International Nanomedicine and Drug Delivery Symposium (NanoDDS'09), J. Control. Release 146, 163, 2010.
Kinam Park: Focused ultrasound for targeted nanoparticle delivery to tumors, J. Control. Release 146 (2010) 263.
Kinam Park: Carbonate apatite-facilitated intracellular delivery of siRNA, J. Control. Release 147 (2010) 1.
Kinam Park: Critical role of molecular imaging for substantially improved anticancer therapy, J. Control. Release 147 (2010) 153.
Kinam Park: Effect of shape and size of polymer particles on cellular internalization, J. Control. Release 147 (2010) 313.
Kinam Park: Paclitaxel-loaded nanoparticles by temperature-induced phase transition, J. Control. Release 148 (2010) 265.
Kinam Park: Achilles heels and Trojan horses against drug-resistant tumor cells, J. Control. Release 149 (2010) 91.
Kinam Park: Enhanced delivery to endothelial lysosomes by ICAM-1-targeted nanocarriers, J. Control. Release 149 (2011) 207-208.
Kinam Park: Selective endothelial targeting of stealthed adenovirus, J. Control. Release 150 (2011) 127.
Kinam Park: Noninvasive imaging of MT1-MMP-positive tumors, J. Control. Release 150 (3) (2011) 237.
Kinam Park: Systemic anti-tumor activity of liposomal glucocorticoids, J. Control. Release 151 (1) (2011) 1.
Kinam Park: Mechanism of cross-presentation of microencapsulated antigen, J. Control. Release 151 (3) (2011) 219.
Kinam Park: Injectable hyaluronic acid hydrogel for bone augmentation, J. Control. Release 152 (2) (2011) 207.
Kinam Park: Improving the reach of vaccines to low-resource regions with a needle-free vaccine delivery device and long-term thermostabilization, J. Control. Release 152 (3) (2011) 329.
Kinam Park: Unraveling the penetration: Model giant plasma membrane vesicles for study of cell-penetrating peptides, J. Control. Release 153 (2) (2011) 105.
Kinam Park: Hexagonal prism nanocarriers for mitigated phagocytosis, J. Control. Release 154 (1) (2011) 1.
Kinam Park: Administration route and carrier dependent effects on vaccine efficacy: Implications for vaccine design, J. Control. Release 154 (2) (2011) 109.
Kinam Park: Shockwave-ruptured nanopayload carriers (SHERPAs) for ultrasound-triggered drug release, J. Control. Release 155 (3) (2011) 343.
Kinam Park: Nanocomposite microparticles for injectable cell scaffolds, J. Control. Release 156 (1) (2011) 1.
Kinam Park: Cardioprotective properties of Tat-BH4 and Pip2b-BH4 in vivo, J. Control. Release 156 (2) (2011) 117.
Kinam Park: IVIVC for circulation kinetics of liposomes, J. Control. Release 156 (2011) 275.
Kinam Park: Albumin: A versatile carrier for drug deliverys, J. Control. Release 157 (2011) 3.
Kinam Park: Microbubble ultrasound-guided targeted delivery to tumors, J. Control. Release 157 (2011) 167.